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Long term effects of depo shot?
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Long term effects of depo shot?
More serious side effects, such as bone loss, can also occur with use. The number one complaint was weight gain. When used perfectly, the birth control shot effectiveness is more than 99%, meaning less than 1 out of every 100 people who use it will get pregnant each year. pain or discomfort in the arms, jaw, back, or neck. They give you the injection in either your upper arm or buttock. The median duration of Depo-Provera use was 6 Continuation rates were 71% at 3 months, 48% at 6 months, 27% at 12 months, and 15% at 18 months. Wildlife photographer Michel d’Oultremont explains how he captures his best shots of animals in the wild. Loss of movement in any part of your body. Depo-Provera, commonly referred to as the birth control shot, is the brand name of the medication depot medroxyprogesterone acetate, or DMPA for short. It is usually used in people who have taken the form of haloperidol that is taken by mouth. During that time you may also experience other side effects, including more bleeding, as your body rids itself of the chemicals & sorts itself out (rebalances your hormones). In theory, the potential for adverse skeletal effects from progestin-only contraceptives other than DMPA may also be less. Amid the endless pandemic, it’s. Shoulder injury related to vaccine administration is an under-reported, preventable series of events caused by incorrect technique or landmarking for intramuscular deltoid injections. It contains medroxyprogesterone acetate, which is similar to the natural progesterone produced by the ovaries during the second half of the menstrual cycle. Apr 1, 2024 · Liver disease, severe—Depo®-Testosterone should not be used in patients with these conditions A nurse or other trained health professional will give you this medicine in a medical facility. Condoms might factor into vaginal irritation and other. Another disadvantage of Depo Provera ® is that the injection cannot be removed if side effects or health concerns arise. Depo-Provera Contraceptive Injection should be used as a long-term birth control method (e longer than 2 years) only if other birth control methods are inadequate. Depo-Medrol® and some strengths of Solu-Medrol® injection should not be used in premature infants. Depo-Medrol benefits of methylprednisolone, especially if it is to be injected near your spine (epidural). But under Obamacare, you can get a flu shot somewhere else for free. A Black Box warning is the FDA's warning way of notifying health care providers that a serious side effect is possible ( Food and Drug Administration, 2004 Lupron Depot is a gonadotropin releasing hormone (GnRH) agonist hormone therapy approved by the FDA for the palliative treatment (to relieve pain and other symptoms) of advanced prostate cancer. Methylprednisolone (brand names: Medrol®, Depo-Medrol®, A-Methapred®, Solu-Medrol®) is a glucocorticoid steroid medication used to treat many inflammatory conditions, pets with adrenal gland disease, and pets with immune-mediated diseases. Includes Eligard side effects, interactions and indications. However, many people have no side effects or only have minor side effects. Medicine Matters Sharing successes, challenges and daily happenings in the Department of Medicine Nadia Hansel, MD, MPH, is the interim director of the Department of Medicine in th. BMD should be evaluated when a woman needs to continue to use Depo-Provera CI long-term. My boobs are extremely sore and I am having a mixture of. loss of appetite nausea. Learn about the side effects of medroxyprogesterone, from common to rare, for consumers and healthcare professionals. It is given as a shot (injection) every 3 months. Wildlife photographer Michel d’Oultremont explains how he captures his best shots of animals in the wild. It has some adverse effects like changes in menstrual pattern, loss in bone mineral density and risk of weight gain. Inflammation and problems with the immune system can also happen. Learn about side effects, warnings, dosage, and more. The most common side effects of Depo-Provera CI include: irregular vaginal bleeding, such as lighter or heavier menstrual bleeding, or continued spotting; weight gain. BMD should be evaluated when a woman needs to continue to use depo-subQ provera 104 long-term. That’s about every 3 months, or 4 times a year. Long-term use of Depo-Provera may cause you to lose bone mineral density, which makes you more likely to get. unpleasant breath odor. • After you stop Depo, it takes a few months for your fertility to return to normal. DEPO-MEDROL is an anti-inflammatory glucocorticoid for intramuscular, intra-articular, soft tissue or intralesional injection. There are long-term options that can last weeks, months and even years. Methylprednisolone (brand names: Medrol®, Depo-Medrol®, A-Methapred®, Solu-Medrol®) is a glucocorticoid steroid medication used to treat many inflammatory conditions, pets with adrenal gland disease, and pets with immune-mediated diseases. I got the Depo shot on Feburary 8th, 2017. What will it be like when the kids are gone? Off to college With new journey partners. Your doctor will need to see you on a regular basis while you are using Depo-Provera CI. pain, tenderness, or swelling of the foot or leg. A link from Telegraph A link from Telegraph Nicolas Mockford, an executive at ExxonMobil, was shot dead on a Brussels suburb street on Oct Initially police said they were not. Now, there's a growing concern among health professionals that some people who are taking the drugs long-term shouldn't be—needlessly subjecting themselves to side effects and potential health risks. Additionally, medroxyprogesterone is used for abnormal uterine bleeding due to ovulatory dysfunction, prevention of endometrial hyperplasia, pain related to endometriosis, and in. As far as infertility goes, Ruiz says, the Depo shot "has a bit of a cumulative effect. A link from Telegraph A link from Telegraph Nicolas Mockford, an executive at ExxonMobil, was shot dead on a Brussels suburb street on Oct Initially police said they were not. One-shot Games vs. Depo®-Testosterone contains benzyl alcohol which may cause serious reactions to newborn, premature, or low-birthweight infants. This keeps a fertilized egg from attaching to it, which is a part of pregnancy. Although Depo-Provera continuation rates among adolescents are low, over a third of discontinuers may restart the method. First-generation LAIs have more severe side effects, including tardive dyskinesia, which can cause involuntary muscle movements The recommended dose is 150 mg of Depo-Provera CI every 3 months (13 weeks) administered by deep intramuscular (IM) injection using strict aseptic technique in the gluteal or deltoid muscle, rotating the sites with every injection. Injectable DMPA 400 to 1000 mg intramuscularly per week is recommended initially. There are two types of Depo-Provera and both prevent pregnancy about 94% of the time, if taken on time. It is not known what the effects will be on bones when used in teenaged and young adult women. Detailed drug Information for Depo-Provera Contraceptive. The medication used in depot injections is the same as other forms of the drug, such as tablets or liquid. The effects are gone as soon as they're stopped or removed. When weighing up the risks and benefits of long term antipsychotic treatment for the individual patient with schizophrenia, the clinician must take into account the nature, severity and frequency of past relapses, and the degree of distress and disability related to any adverse effects. If you get the birth control shot (also known as Depo-Provera) within the first 7 days after the start of your period, you're protected from pregnancy right away. However, a recent review of the drug's long-term effects on bone mineral density (BMD) by the FDA and Pfizer Inc. Your health care provider prescribed a blood thinning medicine. In that case, you need to take the recommended breaks every couple of years. Along with increasing availability and utilization of contraception, It is also important to confirm that the effects of contraception use on resumption of fertility after discontinuation However currently evidences on resumption of fertility after contraception. Contraceptive injections (medroxyprogesterone) Find out how medroxyprogesterone injections are used for contraception and how you have them. That’s about every 3 months, or 4 times a year. We performed this study on 60 healthy Nepalese women who had been using DMPA for more than 2 yr and age- and weight-matched control subjects. pain or discomfort in the arms, jaw, back, or neck. BMD should be evaluated when a woman needs to continue to use Depo-Provera CI long-term. 02 mg of ethinyl estradiol for 10 days. Long-term side effects may refer to side effects which appear after you've taken the drug for a long time As such, negative long-term effects of Botox are far and few between, and short term negative effects are more likely. Other risk factors would include low body weight, especially with eating disorders. sudden, severe weakness or numbness in the arm or leg. The injection will prevent pregnancy for three months and the birth control effects begin as soon as you have your first shot. Rare but serious side effects may occur with epidural use. I have noticed since starting Depo that I have more vaginal discharge, more acne, and my boobs tend to be sore more often. Botox could give you another shot at looking young. Depo-Provera is an injection that prevents pregnancy for 3 months at a time. Over weeks to months, the pain will calm down, and you will slowly return to your. delco times obituaries today What will it be like when the kids are gone? Off to college With new journey partners. A careful re-evaluation of. every 3 months in the clinic or at home witha It may be called "depo" or "the shot" rogestin-only method which means that it's safe for most people. Detailed drug Information for Depo-Testosterone. Everything was great for the first month… my period usually comes on at the end of each month… the following month (Nov. Depo-Medrol may cause serious side effects. Depo-Provera (medroxyprogesterone acetate) is a form of birth control. In particular, symptoms reported by women using depot medroxyprogesterone acetate (DMPA) include abnormal bleeding, dysmenorrhea, hair loss, hirsutism, nausea, acne, headaches, mood changes, decreased libido, fatigue, breast discomfort, and bloating. high blood pressure Recently, the long-term 9-year effectiveness of the bivalent vaccine against HPV16/18 and 31/45/52 infection was reported in Japanese women aged 25-26 years. noisy, rattling breathing. social ministry workers face termination. As with any IM injection, to avoid an inadvertent subcutaneous injection, body habitus should be assessed prior to. It contains a synthetic hormone called progestin. This includes testosterone, a hormone that helps prostate cancer cells grow and spread. That’s about every 3 months, or 4 times a year. Jun 16, 2021 · To go off of this form of birth control, just don’t get your next shot. Each visit after the first one may cost between $0 and $150. What will it be like when the house is quiet, there. Rare but serious side effects may occur with epidural use. Learn about the side effects of HCG (chorionic gonadotropin (hcg)), from common to rare, for consumers and healthcare professionals. part time gym jobs Depo-Medrone may be used locally or systemically, particularly where oral therapy is not feasible particularly if long-term, should be planned bearing in mind the more serious consequences of the common side-effects of corticosteroids in old age and close clinical supervision is required (see Special warnings and special precautions for. sores, ulcers, or white spots on the lips or tongue or inside the mouth. The study objective was to collate evidence on clinical effectiveness of etonogestrel subdermal implant (ESI), continuation rate and side effect profile among eligible women of reproductive age group, as compared to levonorgestrel. Contraceptive injection. Find patient medical information for Depo-Provera Contraceptive intramuscular on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. If an injection is late or missed, pregnancy. Depo-Provera (Medroxyprogesterone (Injection)) received an overall rating of 4 out of 10 stars from 927 reviews. There are long-term options that can last weeks, months and even years. hot flashes muscle, joint, or bone pains redness or irritation at site where injected or implanted. This article discusses how to ease the pain of shots for babies. The benefit starts within 3 to 6 months after starting the pill. Mood swings, severe depression, OCD, severe anxiety, loss of sex drive, constant spotting, loss of attraction to my BF, and. Depo Provera is a long acting contraceptive hormone injection for women that contains a progestogen (sex hormone) called medroxyprogesterone acetate. The use of depo-subQ provera 104 is not recommended as a long-term (i, longer than 2 years) birth control method or medical therapy for endometriosis-associated pain unless other options are considered inadequate. If an injection is late or missed, pregnancy. But when you do, you might have a sore shoulder for a cou. DEPO-MEDROL Sterile Aqueous Suspension contains methylprednisolone acetate which is the 6-methyl derivative of prednisolone. Depo-Medrol® and some strengths of Solu-Medrol® injection should not be used in premature infants. skin rash, hives, or itching. The first citation for the t. Placebo-controlled studies of hormonal IUD impact on mood are needed, particularly in women with PMS/PMDD. Find patient medical information for Kenalog injection on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. big toy car A long-acting injectable (LAI) for bipolar disorder is an intramuscular shot that provides a sustained release of medication over a period of time, typically weeks to months The use of Depo-Provera CI is not recommended as a long-term (i, longer than 2 years) birth control method unless other options are considered inadequate. Normally, we don't see a big change in weight or blood pressure unless someone already had these issues in the past. A healthcare provider will give you this injection in a hospital or clinic setting. Glucose tolerance was impaired with higher intolerance at. HbA1c levels have been reported to be significant in terms of the status of glycemic control for 3 months [19,30]. Talk with your nurse or doctor about any other health conditions you have and you can decide together if the shot is a good fit for. 8 Find patient medical information for Lupron Depot (3 month) intramuscular on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Your doctor will need to see you on a regular basis while you are using Depo-Provera CI. 1 Its primary effect is to reduce the chance of ovulation by limiting follicle stimulating hormone and luteinizing hormone secretion. Leaking breasts can also happen from time to time. I've historically had extremely heavy and painful menstrual cycles, with large. The most common exposure is through a small break in the skin. The FSRH's position is that the risks of the method outweigh the benefits in women with multiple risk factors for cardiovascular disease. There are long-term options that can last weeks, months and even years.
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The injections should be as painless as possible. Safer Shot News: This is the News-site for the company Safer Shot on Markets Insider Indices Commodities Currencies Stocks It’s flu shot season again! You’ve no doubt seen the signs saying “walk right in, get a flu shot!” Before you impulsively obey that ad, find out the best places to get your flu sho. A crash course on the shot (depo provera), including its side effects, usage, and patient preferences. There are two types of Depo-Provera and both prevent pregnancy about 94% of the time, if taken on time. Depot medroxyprogesterone acetate is the injectable (given by shot) form of a lab-made hormone called medroxyprogesterone acetate. Depo-Provera is an injection that prevents pregnancy for 3 months at a time. Progestin stops you from getting pregnant by preventing ovulation. It has some adverse effects like changes in menstrual pattern, loss in bone mineral density and risk of weight gain. The longer you take it, the lower your risk. But when you do, you might have a sore shoulder for a cou. Pregnancy prevention shots like Depo-Provera ® essentially provide your body with a hefty dose of birth control intended to stay in your system for three months — which makes going off this. Lower back ache is common, as your pelvis ligaments soften, ready for a growing baby. Males can have sexual intercourse but do not want to. The injections should be as painless as possible. Sometimes pain relief is short term. Learn about the side effects of HCG (chorionic gonadotropin (hcg)), from common to rare, for consumers and healthcare professionals. Long-term use of Depo-Provera may cause you to lose bone mineral density, which makes you more likely to get. drew steimel Your doctor may recommend you use this medicine long-term. That data is already in, says Paul Goepfert, M, and vaccine experts are confident that there won't be long-term side effects. Contraceptive injection Find out about the contraceptive injection, including who can use it, how well it works and possible side effects. It also works by making cervical mucus thicker. you have an accident or become unconscious. Depo-Provera also lowers the risk, especially if you use it for more than 3 years. When weighing up the risks and benefits of long term antipsychotic treatment for the individual patient with schizophrenia, the clinician must take into account the nature, severity and frequency of past relapses, and the degree of distress and disability related to any adverse effects. Here's what to expect from each treatment. At the same time as the Canadian statement, the U Federal Food and Drug Administration issued a "Black Box" warning about the long-term use of Depo-Provera and its effects on BMD. Both brands of methylprednisolone injection contain benzyl alcohol, which may cause serious unwanted effects in premature infants. Our study aims to determine the effects of long-term use of DMPA on lipid metabolism. The population studied ranges in age from 15 to 51 years, of which 46% were White, 50% Non-White, and 4 Side Effects. This synthetic hormone treats symptoms of prostate cancer, early-onset puberty and other hormone-related conditions. Corticosteroid injections into articular, periarticular, or soft tissue. But for most people, the implant makes their periods way lighter. Of the women who met the original inclusion criteria, 79 were either lost. Sep 6, 2002 · Bone density loss increases the risk for osteoporosis, a disease primarily of old age in which bones become fragile and are more likely to break. That can be a mixture of bleeding, spotting (pink/brown/red), or no bleeding at all, until you've had 2 or 3 shots, & then you typically find that your periods stop, altogether, until you come off Depo Provera. sores, ulcers, or white spots on the lips or tongue or inside the mouth. Weights and heights were measured for all children, and information on signs of puberty obtained for children a … Patient was informed of diagnosis of atrophic vaginitis likely secondary to long-term depo-provera use. nebraska football That’s about every 3 months, or 4 times a year. Depo-Provera CI can cause serious side effects, including: Effect on the bones: See " What is the most important information I should know about Depo-Provera CI ?". By clicking "TRY IT", I agree to receive newslet. slow growth in children. Nausea, vomiting, heartburn, headache, dizziness, trouble sleeping, appetite changes, increased sweating, acne, or pain/redness/swelling at the injection site may occur Jun 9, 2023 · Side effects of hormone therapy for prostate cancer can include: Loss of muscle mass Loss of sex drive. How the birth control shot (Depo-Provera) affects people with PMS or PMDD Depo Provera is a shot administered every three months, which prevents ovulation and thickens cervical mucus to prevent pregnancy. If you have medroxyprogesterone contraceptive injections for a long time, your bones may become weaker or more fragile (osteoporosis). puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue. 70% of those discontinuing the method for irregular. How long the depo shot stays in your system or lasts after you stop using it is a little bit different for everyone. These side effects depend both on the type of steroid prescribed and on the dosage administered, and. Depo-Provera, or the birth control shot, and birth control pills are two types of contraceptives that use hormones to prevent pregnancy. Forty women (21-44 years old) who used DMPA for contraception for <1, 1-2 and >5 years, in addition to 20 age-matched healthy women (nonusers), participated in this study Children exposed to the injectable contraceptive Depo-Provera (DMPA) during pregnancy (N = 1,207), and/or during breastfeeding (N = 1,215) were exposures during pregnancy or breastfeeding. you have an accident or become unconscious. buffalo wild wings workday login In adolescents, interpretation of BMD results should take into account patient age and skeletal. Condition: Endometriosis0 Ease of Use if you're having trouble with your hormones being balanced, and suffer from dysmenorrhea that doesn't seem to be helped by any pill, patch or implant, then depo may be for you. When used correctly, it is as much as 99 Other possible side effects include nausea, weight gain, headaches, sore breasts, or depression. Back pain: What you can expect from steroid injections. Depo-Provera should also be used with caution if you are between 18 and 40 and have other risk factors for osteoporosis, especially if you take glucocorticoid (steroid) tablets (glucocorticoid tablets are used to treat inflammation in conditions such as asthma). sudden, unexplained shortness of breath. Weights and heights were measured for all children, and information on signs of puberty obtained for children a … Patient was informed of diagnosis of atrophic vaginitis likely secondary to long-term depo-provera use. hot flashes muscle, joint, or bone pains redness or irritation at site where injected or implanted. The birth control shot often causes period changes. Depo-Provera Injectable Suspension. Depo-Medrone may be used locally or systemically, particularly where oral therapy is not feasible particularly if long-term, should be planned bearing in mind the more serious consequences of the common side-effects of corticosteroids in old age and close clinical supervision is required (see Special warnings and special precautions for. The effects of Depo-Provera are greatest in the first 2-3 years of use. A contraceptive implant is a flexible plastic rod about the size of a matchstick that is placed under the skin of the upper arm. May 12, 2021 · Depo-Provera can cause you to experience a number of side effects, including: Irregular menstrual periods or no periods at all, which is a safe benefit of the shot Nervousness Acne. Three months is the same as 12 to 14 weeks. Many Americans say they want to "make sure the shot is safe" before getting vaccinated. Pregnancy prevention shots like Depo-Provera ® essentially provide your body with a hefty dose of birth control intended to stay in your system for three months — which makes going off this. Teenage years are the most important years to gain bone strength. Medroxyprogesterone acetate ( MPA ), also known as depot medroxyprogesterone acetate ( DMPA) in injectable form and sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type.
Talk with your doctor about this risk. Depo-Provera (medroxyprogesterone acetate) is a form of birth control. severe, sudden headache. shortness of breath. A nurse or a doctor will give you the shot every 12-13 weeks, which is every three months. Depot medroxyprogesterone acetate is a highly effective contraceptive that affords privacy (similar to an intrauterine system) and has a convenient dose schedule of four times per year, making it appealing to many. Side Effects. Some people should not get certain vaccines or should wait before getting them. penske truck lease cost The birth control shot works similarly to the pill by preventing. Answers. 4% (15/279) in the unvaccinated group, showing a significant difference ( p = 0. About two-thirds of the women who used Depo-Provera CI in the clinical trials reported a weight gain of about. The birth control shot (sometimes called Depo-Provera, the Depo shot, or DMPA) contains the hormone progestin. Milk, cheese and leafy greens contain lots of calcium. Feeling dizzy, tired, or weak Constipation. gadsden alabama craigslist Wildlife photographer Michel d’Oultremont explains how he captures his best shots of animals in the wild. Effects on Lactation: Several studies have attempted to measure the effects of Depo Provera on milk quality and volume and on duration of lactation. It also discourages sexual fantasies and eradicates sexual obsessions. In the present day, the FDA has recognized the use of estroprogestative pills as a safe. Depo-Medrol benefits of methylprednisolone, especially if it is to be injected near your spine (epidural). fastpitch softball tournaments The glass is small and designed to hold a measure of liquor. Leaking breasts can also happen from time to time. These side effects may go away during treatment as your body adjusts to the medicine. Former President Donald Trump was arraigned but didn't have his mug shot taken. Side effects, especially menstrual irregularities (25%) and weight gain (19%), were the main reason for Depo-Provera discontinuation.
How long can I use vaginal estrogen? — As low-dose vaginal estrogen is associated with few adverse effects, it can probably be used indefinitely, although there are no long-term studies to provide data about the effects over many years. The medication, administered as a shot deep in the muscle tissue, works for approximately 12 to 14 weeks. This article discusses how to ease the pain of shots for babies. antipsychotics are significantly more effective than oral antipsychotics. Learn about the side effects of HCG (chorionic gonadotropin (hcg)), from common to rare, for consumers and healthcare professionals. slow or fast heartbeat. They can be used to treat problems such as joint pain, arthritis, sciatica and inflammatory bowel disease. The therapeutic effects of corticosteroids are, however, often temporary, with some studies suggesting no long-term difference between corticosteroids and placebo. swelling of the eyelids, face, fingers, lips, hands, feet, or lower legs. Using Depo-Provera continuously for more than two years may increase the risk of osteoporosis, which could increase your risk of weak, porous bones. Potential side effects of DMPA include bone density. Potential side effects of DMPA include bone density. walmart grocery order online Patient was instructed to discontinue depo-provera, given prescription to start combined oral contraceptive pills and vaginal estrogen cream. My boobs are extremely sore and I am having a mixture of. However, considering the evolving understanding of CRSwNP and the chronicity of this condition, the short-lived benefits of systemic GCS therapy need to be balanced with the long-term potential AE's which are discussed below. Wildlife photographer Michel d’Oultremont explains how he captures his best shots of animals in the wild. high blood pressure Recently, the long-term 9-year effectiveness of the bivalent vaccine against HPV16/18 and 31/45/52 infection was reported in Japanese women aged 25-26 years. DMPA contains progestin, a synthetic hormone. All medicines may cause side effects, but many people have no, or minor, side effects. Potential side effects of DMPA include bone density. At Wayne’s Campus Hea. About half of people stop getting their period while they're on the shot (don't worry, this is totally safe). It is similar to but slightly more potent than prednisone / prednisolone. Undesirable effects may be minimised by using the lowest effective dose for the minimum period (see section 4 Depo-Medrone vials are intended for single dose use only. It contains a synthetic hormone called progestin. This article discusses how to ease the pain of shots for babies. You're probably aware of the Pill and getting an IUD, and you may also have heard of the Depo-Provera. In the present day, the FDA has recognized the use of estroprogestative pills as a safe. This is a fat-filled area that covers the spinal cord to protect it and the surrounding nerves from damage. Depo-Provera has been used throughout the world for decades and remains a safe and effective method of birth control, the FDA said in a statement. woodstock al What's y'all's opinion? Pelvic pain due to endometriosis can be treated with medical therapy, surgical intervention, or a combination of both. The most common birth control implant side effect is spotting (light bleeding or brown discharge), especially in the first 6-12 months. It is made of synthetic progesterone and works by inhibiting monthly ovulation. So, in reality, about 4 out of every 100 shot users will get. Depot medroxyprogesterone acetate (DMPA) injections are an effective form of hormonal contraception DMPA (Depo-Provera) is a fully funded form of progestogen-only contraception administered via intramuscular injection. Depo-Provera Injectable Suspension. Detailed drug Information for Depo-Medrol. A nurse or a doctor will give you the shot every 12-13 weeks, which is every three months. The dosage will be adjusted or stopped based on your response or lack of response to the medication. If improvement is noted within a few weeks or months and the disease appears stabilized, it may be possible to maintain improvement with as little as 400 mg per month. 1 Its primary effect is to reduce the chance of ovulation by limiting follicle stimulating hormone and luteinizing hormone secretion. Bone thinning, which can lead to broken bones Less body hair, smaller genitals and growth of breast tissue. Depo-Provera also lowers the risk, especially if you use it for more than 3 years. You must have your shot of Depo-Provera CI® contraceptive injection) or Depo-Subq Provera 104® every 12 to 14 weeks to prevent pregnancy. At the same time as the Canadian statement, the U Federal Food and Drug Administration issued a "Black Box" warning about the long-term use of Depo-Provera and its effects on BMD.